Respiratory Metabolism of Mammalian Eggs.

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Abstract
The O2 uptake of fertilized rabbit ova was measured in the Cartesian diver and Warburg apparatus at different stages of development (one-cell to blasto-cysi stage). O2 uptake remains constant from the one-cell to the late morula stage. There is a sudden rise at the early blasto-cyst stage. This rise in respiratory rate continues and the late preimplantation blastocyst (6 days post coitum) respires about 1600 times as rapidly as does the late morula. There is no corresponding increase in tissue volume. Apparently there is a change in metabolic pathways.

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