Permeability of hyaluronic acid solutions
Open Access
- 1 December 1980
- journal article
- research article
- Published by Wiley in Arthritis & Rheumatism
- Vol. 23 (12) , 1371-1375
- https://doi.org/10.1002/art.1780231207
Abstract
The permeability of hyaluronic acid solutions was measured in a chamber closed at each end by semipermeable membranes. Permeability was strongly concentration dependent below 1.0 gm% hyaluronic acid. Small changes in the ionic environment of 1.0 gm% hyaluronic acid solutions also altered permeability. The permeability of such solutions decreased by a factor of 4.7 in the presence of as little as 5 mM calcium ion and showed optimum permeability at pH 7.0. The pH optimum was not noted in hyaluronic acid preparations known to contain only small amounts of protein.This publication has 13 references indexed in Scilit:
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