THE HYDROLYSIS OF ACETYLSALICYLIC ACID FROM AQUEOUS SUSPENSION
- 1 September 1958
- journal article
- Published by Oxford University Press (OUP) in Journal of Pharmacy and Pharmacology
- Vol. 10 (1) , 363-369
- https://doi.org/10.1111/j.2042-7158.1958.tb10316.x
Abstract
An investigation of the kinetics of the hydrolysis of acetylsalicylic acid from aqueous suspension is described. The net reaction is one of solution of the solid followed by hydrolysis in solution, so that the rate of reaction is dependent on the concentration of the saturated solution. Under conditions where the solubility of acetylsalicylic acid is small in comparison with the quantity in suspension, a zero order reaction results. The B.P.C. mixture is discussed.Keywords
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