Ectopic Adrenocorticotropin Production: Disappearance after Removal of Inflammatory Tissue*
- 1 April 1984
- journal article
- research article
- Published by The Endocrine Society in Journal of Clinical Endocrinology & Metabolism
- Vol. 58 (4) , 654-658
- https://doi.org/10.1210/jcem-58-4-654
Abstract
A patient presented with the clinical and laboratory features of the ectopic ACTH syndrome. No ACTHproducing tumor was found, and bilateral adrenalectomy was performed to correct the hypercortisolism. Six months later, the removal of a pesudotumor containing only fat and inflammatory tissue resulted in normalization of both basal plasma ACTH levels and the ACTH feedback response to cortisol infusion. It is suggested that the leukocytes in the inflammatory tissue were the source of the ectopic ACTH production.Keywords
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