A short formal synthesis of paroxetine. Diastereoselective cuprate addition to a chiral racemic olefinic amido ester
- 29 October 2001
- journal article
- research article
- Published by Elsevier in Tetrahedron Letters
- Vol. 42 (44) , 7805-7807
- https://doi.org/10.1016/s0040-4039(01)01666-5
Abstract
No abstract availableKeywords
This publication has 15 references indexed in Scilit:
- Asymmetric syntheses of trans-3,4-disubstituted 2-piperidinones and piperidinesTetrahedron: Asymmetry, 2001
- Synthesis of Enantiopuretrans-3,4-Disubstituted Piperidines. An Enantiodivergent Synthesis of (+)- and (−)-ParoxetineThe Journal of Organic Chemistry, 2000
- Diastereoselective Synthesis of trans- 4-Arylpiperidine-3-carboxylic Acid Derivatives from 4-Aryl-1,4-dihydropyridineHETEROCYCLES, 1999
- ParoxetineDrugs, 1998
- Synthesis and 5HT Modulating Activity of Stereoisomers of 3-Phenoxymethyl-4-phenylpiperidines.Acta Chemica Scandinavica, 1996
- The synthesis of [14C]‐3S,4R‐4‐(4‐fluorophenyl)‐3‐(3,4‐methylenedioxyphenoxymethyl)piperidine hydrochloride (BRL 29060A), and mechanistic studies using carbon‐13 labellingJournal of Labelled Compounds and Radiopharmaceuticals, 1993
- Binding Potency of Paroxetine Analogues for the 5-Hydroxytryptamine Uptake ComplexJournal of Pharmacy and Pharmacology, 1992
- A Diels–Alder approach to functionalized cis-hydroisoquinolines. Attempts to prepare a tricyclic core unit of manzamine AJournal of the Chemical Society, Perkin Transactions 1, 1991
- The absolute configurations and pharmacological activities of the optical isomers of fluoxetine, a selective serotonin-uptake inhibitorJournal of Medicinal Chemistry, 1988
- Preparation of .beta.-keto esters by 4-DMAP-catalyzed ester exchangeThe Journal of Organic Chemistry, 1985