Lead Speciation by HPLC--ICP--AES and HPLC--ICP--MS
- 1 March 1991
- journal article
- research article
- Published by Oxford University Press (OUP) in Journal of Chromatographic Science
- Vol. 29 (3) , 98-102
- https://doi.org/10.1093/chromsci/29.3.98
Abstract
Speciation of inorganic lead (Pb2+) and several trialkyllead species (trimethyllead chloride [TML], triethyllead chloride [TEL], and triphenyllead chloride [TPhL]) is investigated using high-performance liquid chromatography (HPLC) with detection by both inductively coupled plasma emission spectroscopy (ICP—AES), and inductively coupled plasma mass spectrometry (ICP—MS). Reversed-phase, ion-pairing, and ion-exchange HPLC modes are studied. Optimal chromatographic conditions for ICP—AES detection include a reversed-phase separation utilizing a step gradient from 10 to 70% methanol. However, the gradient has been found to destabilize the plasma when using ICP—MS detection. An isocratic separation with a 30% methanol mobile phase has been found to be the best compromise between plasma stability and chromatographic resolution. Detection limits using ICP—MS detection are 3 orders of magnitude improved over ICP—AES detection.Keywords
This publication has 0 references indexed in Scilit: