Definition of disease-free survival: this is my truth–show me yours

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Abstract
In the wake of significant advances made in the treatment of advanced colorectal cancer, progress has also been made in the adjuvant treatment of this disease, for example with oxaliplatin having been shown to add benefit to 5-flurouracil (5-FU)-based adjuvant chemotherapy in two major studies [1, 2]. These studies used two different definitions of 3-year disease-free survival (DFS) as the primary end point, and reflect the contemporary interest in different possible definitions of this outcome measure relative to its use as a surrogate for overall survival (OS), the latter traditionally regarded as the ultimate measure of treatment benefit.

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