Topical hemostatic agents for bone bleeding in humans. A quantitative comparison of gelatin paste, gelatin sponge plus bovine thrombin, and microfibrillar collagen.
- 1 June 1978
- journal article
- research article
- Published by Wolters Kluwer Health in Journal of Bone and Joint Surgery
- Vol. 60 (4) , 454-456
- https://doi.org/10.2106/00004623-197860040-00004
Abstract
The three topical hemostatic agents--gelatin paste, microfibrillar collagen, and gelatin sponge soaked in thrombin--individually were effective in reducing bleeding from cancellous bone, as tested on the femoral surface of trochanteric osteotomies during total hip replacement. During a three-minute interval, the spontaneous reduction in bleeding in eight control hips to which no agent was applied was 11 per cent. Gelatin paste gave a reduction of 85 per cent; gelatin sponge soaked in thrombin, a reduction of 75 per cent; and microfibrillar collagen, a reduction of 47 per cent. None of these agents interfered with healing of the trochanteric osteotomy.This publication has 1 reference indexed in Scilit:
- Total hip replacement and femoral-head bone-grafting for severe acetabular deficiency in adultsJournal of Bone and Joint Surgery, 1977