7-O-Methylhorminone and Other Cytotoxic Diterpene Quinones from Lepechinia bullata

Abstract
Three cytotoxic diterpene quinones, 6,7-dehydroroyleanone[1], horminone [2], and 7-O-methylhorminone [3], were isolated from an MeOH extract of Lepehinia bullata after bioassay-directed fractionation. Compound 3 is a new compound whose structure was determined through spectroscopic analysis.