Allogeneic Leukocytes as a Possible Factor in Induction of AIDS in Homosexual Men

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Abstract
To the Editor: The current leading etiologic candidate for acquired immune-deficiency syndrome (AIDS) is a new infectious agent.1 However, it is unlikely that this complex syndrome is the result of a single factor, and investigators of AIDS should consider additional possibilities.2 A possibility that has been mentioned briefly but not considered in detail is that allogeneic leukocytes could be a contributing factor in the induction of AIDS among homosexual men.3 , 4 How could allogeneic leukocytes be transferred between homosexuals? This could be achieved in the transfer of semen from active to passive partner by anal intercourse. Human semen can be . . .