In vivo Inhibition of Lipogenesis by Biotin Deficiency.

Abstract
Summary Biotin deficiency in the intact chick resulted in increased incorporation of sodium acetate-1-C14 into respiratory CO2 and decreased incorporation into carcass long chain fatty acids. Biotin deficiency had no effect on the incorporation of malonic-2-C14 acid. The total fatty acid content of the carcass was decreased and the proportion of 16-carbon to 18-carbon fatty acids was increased by biotin deficiency.

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