New antibiotics, carbazomycins A and B. I. Fermentation, extraction, purification and physico-chemical and biological properties.

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Abstract
An unidentified Streptomyces, tentatively designated as Strain H 1051-MY 10, produced viomycin and 2 new antibiotics. The new antibiotics were extracted from the cultured mycelia with acetone and transferred to ethyl acetate after acetone was removed in vacuo. The extracted antibiotics were separated into 2 components by alumina column chromatography and named carbazomycins A and B because both antibiotics were proven to contain a carbazole nucleus. The molecular formulae of carbazomycins A and B were determined to be C16H17NO2 and C15H15NO2, respectively. Carbazomycin B was methylated with diazomethane to give carbazomycin A. Carbazomycins inhibited the growth of phytopathogenic fungi and showed weak antibacterial and antiyeast activities.