‘Freezing’ of the Calcium-Regulated Structures of Gizzard Thin Filaments by Glutaraldehyde1
- 1 March 1979
- journal article
- research article
- Published by Oxford University Press (OUP) in The Journal of Biochemistry
- Vol. 85 (3) , 879-881
- https://doi.org/10.1093/oxfordjournals.jbchem.a132404
Abstract
Reconstituted thin filaments (the actin-tropomyosin-leiotonin complex) of chicken gizzard were cross-linked with glutaraldehyde either in the presence or absence of Ca2+. The ability of resultant thin filaments to activate myosin ATPase was ‘frozen’ in the activated or inactivated state, respectively. This result clearly indicates the existence of actin-linked regulation in smooth muscle.This publication has 7 references indexed in Scilit:
- Calcium Sensitivity of Contractile Proteins from Chicken Gizzard Muscle1The Journal of Biochemistry, 1978
- Does Phosphoryiation of Myosin Light Chain Have Direct Relation to Regulation in Smooth Muscle?1The Journal of Biochemistry, 1977
- Ca2+ Regulation in Vascular Smooth Muscle1The Journal of Biochemistry, 1977
- Essential Factor of Gizzard “Troponin” FractionThe Journal of Biochemistry, 1977
- Effect of phosphorylation of smooth muscle myosin on actin activation and Ca2+ regulation.Proceedings of the National Academy of Sciences, 1977
- Actin crosslinked with glutaraldehyde: Evidence to suggest an active role for actin in the regulatory mechanismBiochemical and Biophysical Research Communications, 1976
- A relationship between Ca2+ sensitivity and phosphorylation of gizzard actomyosinBiochemical and Biophysical Research Communications, 1976