One-Pot Synthesis of Thiazolidino [3,2-a] Pyrimidine Derivatives
- 1 July 1991
- journal article
- research article
- Published by Taylor & Francis in Synthetic Communications
- Vol. 21 (14) , 1443-1454
- https://doi.org/10.1080/00397919108016417
Abstract
Reaction of 2-aminothiazoline with an aromatic aldehyde and an activated methylene group (malonitrile, diethylmalonate or ethylcyanoacetate) gave the title compounds. The structures are unambiguously assigned using spectroscopic data and chemical proofs.Keywords
This publication has 6 references indexed in Scilit:
- Synthèse et étude structurale de dérivés substitués en -2 du thiazolidine carboxylate d'éthyle-4 (R)Journal of Heterocyclic Chemistry, 1987
- The Reactions of Benzylmalononitriles with Hydrazine and Hydroxylamine. Synthesis of Pyrazoles, Isoxazoles, and Pyrazolo[1,5-a]-pyrimidine DerivativesSynthesis, 1987
- A Simple Method for the Preparation of 2-Amino-4-aryl-3-cyanopyridines by the Condensation of Malononitrile with Aromatic Aldehydes and Alkyl Ketones in the Presence of Ammonium AcetateSynthesis, 1980
- Syntheses of heterocyclic fused thiazole acetic acids. 2Journal of Medicinal Chemistry, 1976
- Decarbalkoxylations of geminal diesters and β-keto esters in wet dimethyl sulfoxide. Effect of added sodium chloride on the decarbalkoxylation rates of mono- and di-substituted Malonate estersTetrahedron Letters, 1974
- Decarbalkoxylations of geminal diesters, β-keto esters and α-cyano esters effected by sodium chloride in dimethyl sulpoxideTetrahedron Letters, 1973