Changes of Collagen in the Aging and in the Pregnant Uterus of White Rats
- 1 January 1964
- journal article
- research article
- Published by S. Karger AG in Gerontology
- Vol. 10 (2-3) , 137-145
- https://doi.org/10.1159/000211400
Abstract
In the aging uterus the collagen content increases and its concentration becomes threefold. The collagen of virginal uterus shows similar age changes as that of other organs. The percentage of thermolabile collagen decreases from 10-14% in young animals to 5% in 30-40-month-old ones. The newly formed collagen in the pregnant uterus and in placenta is biologically young collagen. In the uterus post-partum the young collagen is removed, only the aged crosslinked collagen resists degradation. After the involutionary period the percentage of labile collagen is at the same low level as in old animals.Keywords
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