Gene controlled condensation in individual chromosomes
- 1 July 1982
- journal article
- research article
- Published by Springer Nature in Cellular and Molecular Life Sciences
- Vol. 38 (7) , 792-794
- https://doi.org/10.1007/bf01972274
Abstract
When cells were irradiated with variable doses of gamma rays, 0.33% showed the appearance of single decondensed chromosomes (SDC) at the moment at which all the other chromosomes of the complement exhibited the normal condensed state corresponding to metaphase stages. Several hypotheses are discussed to explain the origin of SDC. It appears that the most reasonable mechanism to explain our observations is to assume that the process of chromosome condensation is independently controlled in each individual chromosome by a gene/s located in each one of the chromosomes of the complement. A radiation-induced deficiency in one of these genes may produce an impairement in the normal process of condensation of the carrier chromosome which would give rise to SDC.This publication has 9 references indexed in Scilit:
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