Effects of chlorpromazine and electroconvulsive shock on a conditioned emotional response.
- 1 January 1958
- journal article
- research article
- Published by American Psychological Association (APA) in Journal of Comparative and Physiological Psychology
- Vol. 51 (2) , 209-212
- https://doi.org/10.1037/h0042607
Abstract
Retention of a conditioned emotional response (CER) was tested with rats after 14 electroconvulsive shock treatments (ECS), after chlorpromazine and after a combination of both. Control groups were also run. ECS interfered with the retention of the CER and the drug interfered to a lesser extent. The drug led to a partial restoration of the CER which had been virtually eliminated by ECS. The results are discussed in terms of a generalization decrement hypothesis.Keywords
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