A double-blind comparison of venlafaxine and fluoxetine in patients hospitalized for major depression and melancholia
- 1 September 1994
- journal article
- clinical trial
- Published by Wolters Kluwer Health in International Clinical Psychopharmacology
- Vol. 9 (3) , 139-144
- https://doi.org/10.1097/00004850-199409000-00001
Abstract
The antidepressant efficacy and short-term safety of venlafaxine and fluoxetine were compared in 68 patients hospitalized with major depression and melancholia. Venlafaxine was superior in efficacy to fluoxetine; total scores for both the MADRS and the HAM-D were significantly (p < or = 0.05) lower in the venlafaxine group than in the fluoxetine group at Weeks 4 and 6. Overall tolerance was similar for the two treatments.Keywords
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