Temozolomide: a review of its discovery, chemical properties, pre-clinical development and clinical trials
- 31 January 1997
- journal article
- review article
- Published by Elsevier
- Vol. 23 (1) , 35-61
- https://doi.org/10.1016/s0305-7372(97)90019-0
Abstract
No abstract availableKeywords
This publication has 65 references indexed in Scilit:
- The charing cross hospital experience with temozolomide in patients with gliomasEuropean Journal Of Cancer, 1996
- Can positron emission tomography (PET) be used to detect subclinical response to cancer therapy?European Journal Of Cancer, 1995
- Temozolomide reduces the metastatic potential of lewis lung carcinoma (3LL) in mice: Role of α-6 integrin phosphorylationEuropean Journal Of Cancer, 1995
- Possible Involvement of Poly(ADP-Ribosyl) Polymerase in Triggering Stress-Induced ApoptosisExperimental Cell Research, 1994
- From triazines and triazenes to temozolomideEuropean Journal Of Cancer, 1993
- Temozolomide: A new oral cytotoxic chemotherapeutic agent with promising activity against primary brain tumoursEuropean Journal Of Cancer, 1993
- Antitumor imidazotetrazines. 25. Crystal structure of 8-carbamoyl-3-methylimidazo[5,1-d]-1,2,3,5-tetrazin-4(3H)-one (temozolomide) and structural comparisons with the related drugs mitozolomide and DTICJournal of Medicinal Chemistry, 1992
- Role of poly(ADP-ribose) formation in DNA repairNature, 1992
- Antitumor imidazotetrazines. 20. Preparation of the 8-acid derivative of mitozolomide and its utility in the preparation of active antitumor agentsJournal of Medicinal Chemistry, 1990
- Extension of the pre-DNA synthetic phase of the cell cycle as a consequence of DNA alkylation in Chinese hamster cells: A possible mechanism of DNA repairChemico-Biological Interactions, 1971