The Natural History of Impaired Glucose Tolerance in the Pima Indians
- 8 December 1988
- journal article
- research article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 319 (23) , 1500-1506
- https://doi.org/10.1056/nejm198812083192302
Abstract
Among 384 Pima Indians with impaired glucose tolerance according to World Health Organization criteria who were followed for 1.6 to 11.5 years (median, 3.3), non-insulin-dependent diabetes mellitus (NIDDM) developed in 118 (31 percent), glucose tolerance remained impaired in 100 (26 percent), and glucose tolerance returned to normal in 166 (43 percent). The cumulative incidence of NIDDM was 25 and 61 percent at 5 and 10 years, respectively. The risk of development of diabetes was 6.3 times (95 percent confidence interval, 3.8 to 10.6) as high as in a normoglycemic control group (n = 752).This publication has 28 references indexed in Scilit:
- Impaired Glucose Tolerance as a Disorder of Insulin ActionNew England Journal of Medicine, 1988
- Minimal chronic hyperglycemia is a critical determinant of impaired insulin secretion after an incomplete pancreatectomy.Journal of Clinical Investigation, 1988
- Prevalence of diabetes and impaired glucose tolerance and plasma glucose levels in U.S. population aged 20-74 yrDiabetes, 1987
- Impaired glucose tolerance. A target for intervention?Arteriosclerosis: An Official Journal of the American Heart Association, Inc., 1985
- Relationship between the plasma insulin response to oral glucose and insulin-stimulated glucose utilization in normal subjectsDiabetes, 1984
- CORONARY-HEART-DISEASE RISK AND IMPAIRED GLUCOSE TOLERANCE The Whitehall StudyThe Lancet, 1980
- A simplified method using somatostatin to assess in vivo insulin resistance over a range of obesityDiabetes, 1979
- The relationship of insulin response to a glucose stimulus over a wide range of glucose toleranceDiabetologia, 1978
- Diabetes mellitus: incidence, prevalence, survivorship, and causes of death in Rochester, Minnesota, 1945-1970Diabetes, 1976
- Hyperinsulinemia and hypoinsulinemai. Insulin responses to oral carbohydrate over a wide spectrum of glucose toleranceDiabetes, 1975