Corrosion and Thrombogenesis of Cardiovascular Prostheses

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Abstract
In vitro methods have been developed over the last several years to predict the implantation behavior of cardiovascular prostheses. With metals and alloys, their spontaneous potentials in blood or physiological saline, the corrosion behavior in sodium chloride, and surface cleanliness are factors that determine the in vivo patency in animals and humans. The materials used for cardiac valves have a wide passivation region. In vivo monitoring of cardiac prostheses indicates an anodic shift of their rest potentials. Surface contamination appears to cause premature thrombosis and occlusion of cardiac valves.

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