HUMAN IMMUNOGLOBULIN IN A MYELOMA PROTEIN WITH ANTI-GASTRIC PARIETAL-CELL AUTOANTIGEN ACTIVITY
- 1 January 1977
- journal article
- research article
- Vol. 27 (1) , 78-84
Abstract
A previously characterized IgA [immunoglobulin A] .kappa. myeloma protein was isolated and purified. The (Fab) .alpha. fragments of this Ig were obtained. The IgA and Fab fragments reacted in vitro with gastric parietal cells (GPC) using animal gastric sections and with smooth cytoplasmic membranes obtained from rabbit fundus (gastric) mucosa. This was seen macroscopically and by light microscopy and EM. This homogeneous Ig is apparently a typical monoclonal autoantibody.This publication has 12 references indexed in Scilit:
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