Ureteropelvic Junction Obstruction: Its Occurrence in 3 Members of a Single Family

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Abstract
A mother and 2 children with ureteropelvic junction obstruction are described. This is the 8th instance of familial hydronephrosis secondary to ureteropelvic junction obstruction. In this family 10 mo. elapsed between the diagnosis in the 1st sister and the realization that an obstruction also was present in the sibling. With the recognition that ureteropelvic junction obstruction can be familial it is hoped that earlier, possibly correctable cases will be found. An autosomal dominant form of inheritance with variable penetrance is suggested in this family.