Methylprednisolone pulse therapy in severe acute asthma
- 1 February 1987
- Vol. 42 (2) , 154-157
- https://doi.org/10.1111/j.1398-9995.1987.tb02375.x
Abstract
In a group comparative double blind pilot study six asthmatic patients with an acute exacerbation of their disease were randomly treated with either methylprednisolone pulse therapy (MPPT) (1000 mg daily for 3 days) (n = 2) followed by placebo tablets, or standard doses of methylprednisolone (MP) (50 mg daily gradually decreased to zero over 3 weeks) (n = 4). The results showed that the effect of MPPT did not differ from that of standard doses of MP. MPPT has, however, the potential of being preferable to standard treatment with MP, because of easy administration and optimal patient compliance.Keywords
This publication has 9 references indexed in Scilit:
- METHYLPREDNISOLONE PULSE THERAPY INDUCED FALL IN NATURAL KILLER CELL ACTIVITY IN RHEUMATOID ARTHRITISActa Pathologica Microbiologica Scandinavica Series C: Immunology, 2009
- Bradycardia After High-Dose Intravenous Methylprednisolone TherapyScandinavian Journal of Rheumatology, 1986
- A double-blind, randomized clinical trial of methylprednisolone in status asthmaticusArchives of internal medicine (1960), 1983
- Glucocorticoids in acute asthmaThe American Journal of Medicine, 1983
- Double-Blind Evaluation of Methylprednisolone Versus Placebo for Acute Asthma EpisodesPediatrics, 1983
- THE EFFECTS OF INTRAVENOUS PULSE METHYLPREDNISOLONE ON IMMUNOLOGICAL AND INFLAMMATORY PROCESSES IN ANKYLOSING-SPONDYLITIS1983
- A DOUBLE-BLIND PLACEBO-CONTROLLED TRIAL OF METHYLPREDNISOLONE PULSE THERAPY IN ACTIVE RHEUMATOID DISEASEThe Lancet, 1982
- Effect of high‐dose methylprednisolone infusion on polymorphonuclear leukocyte function in patients with systemic lupus erythematosusArthritis & Rheumatism, 1981