Cytokine-induced Prostaglandin E2 Synthesis and Cyclooxygenase-2 Activity Are Regulated Both by a Nitric Oxide-dependent and -independent Mechanism in Rat Osteoblasts in Vitro
Open Access
- 1 January 1999
- journal article
- Published by Elsevier in Journal of Biological Chemistry
- Vol. 274 (3) , 1776-1782
- https://doi.org/10.1074/jbc.274.3.1776
Abstract
No abstract availableKeywords
This publication has 40 references indexed in Scilit:
- Mechanisms of cytokine induced bone resorption: role of nitric oxide, cyclic guanosine monophosphate, and prostaglandinsBone, 1996
- Pulsating Fluid Flow Increases Nitric Oxide (NO) Synthesis by Osteocytes but Not Periosteal Fibroblasts - Correlation with Prostaglandin UpregulationBiochemical and Biophysical Research Communications, 1995
- Cytokines Induce Nitric Oxide Production in Mouse OsteoblastsBiochemical and Biophysical Research Communications, 1994
- Expression of Prostaglandin-Endoperoxide Synthase 1 and Prostaglandin-Endoperoxide Synthase 2 in Human OsteoblastsBiochemical and Biophysical Research Communications, 1994
- Measurement of Interleukin-1 Stimulated Constitutive Prostaglandin G/H Synthase (Cyclooxygenase) mRNA Levels in Osteoblastic MC3T3-E1 Cells Using Competitive Reverse Transcriptase Polymerase Chain ReactionEndocrine Research, 1994
- Involvement of prostaglandin E2 in the inhibition ofosteocalcin synthesis by human osteoblast-like cells in response to cytokines and systemic hormonesBiochemical and Biophysical Research Communications, 1990
- The effects of recombinant human interleukin-1β on cellular proliferation and the production of prostaglandin E2, plasminogen activator, osteocalcin and alkaline phosphatase by osteoblast-like cells derived from human boneBiochemical and Biophysical Research Communications, 1990
- Preferential inhibition of cytokine-stimulated bone resorption by recombinant interferon gammaJournal of Bone and Mineral Research, 1986
- Human purified interleukin‐1 inhibits DNA synthesis and cell growth of osteoblastic cell line (MC3T3‐E1), but enhances alkaline phosphatase activity in the cellsFEBS Letters, 1986
- An interleukin 1 like factor stimulates bone resorption in vitroNature, 1983