Thyroid Iodine Content and Turnover in Euthyroid Subjects: Validity of Estimation of Thyroid Iodine Accumulation from Short-Term Clearance Studies
- 1 May 1969
- journal article
- other
- Published by The Endocrine Society in Journal of Clinical Endocrinology & Metabolism
- Vol. 29 (5) , 721-727
- https://doi.org/10.1210/jcem-29-5-721
Abstract
Measurements of thyroidal (k1) and renal (k2) radioiodine clearances, urinary iodine excretion (qe) and fractional thyroidal radioiodine release rate (αk) were conducted in 18 euthyroid young adult subjects in presumed iodine equilibrium, enabling the thyroid iodine accumulation (A) to be calculated. Thyroid iodide content (TI) was also calculated as: Mean thyroid iodine content assessed in this way (14.9 mg) was in good agreement with thyroid iodine content measured chemically (15 mg) in 8 young adult victims of accidents. These data suggest validity of A estimated in this way.Keywords
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