Restoration of the Ability of Rat Pituitary Homotransplants To Secrete ACTH if Placed Under the Hypothalamic Median Eminence

Abstract
Pituitary homotransplants under the median eminence were capable of inducing a normal adrenal secretion of corticosterone in response to traumatic stress in hypophysectomized rats. Misplacement of the transplants by as little as 1–2 mm or damage to the hypophysial stalk of the host greatly reduced the ability of otherwise viable and healthy transplants to stimulate adrenal secretion. (Endocrinology74: 939, 1964)