Electric current density imaging of mice tumors
- 1 March 1997
- journal article
- research article
- Published by Wiley in Magnetic Resonance in Medicine
- Vol. 37 (3) , 404-409
- https://doi.org/10.1002/mrm.1910370318
Abstract
The use of electric current density imaging (CDI) to map spatial distribution of electric currents through tumors is presented. Specifically, a method previously tested on phantoms was implemented in vivo and in vitro for mapping electric current pulses of the same order of magnitude (j ∽ 2500 A/m2) as in electrochemotherapy through T50/80 mammary carcinomas, B‐16 melanomas and SA‐1 sarcomas. A technically simplified method of electric current density imaging is discussed as well. Three geometries of electrodes (flat‐flat, point‐point, point‐flat) indicate altered electric current distribution for the same tumor. This indicates that the method can be used for monitoring the effects of electrochemotherapy as a function of electrode geometry.Keywords
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