Alveoläre Deposition inhalierter Radioaerosolpartikel bei zentraler und peripherer Atemwegsobstruktion

Abstract
The degree of alveolar deposition of inhaled microparticles, which is affected by airway patency, was studied in 16 asymptomatic smokers with small airways disease. Compared to healthy subjects (n = 12) as well as to patients with chronic obstructive lung disease (COLD, n = 14) significant differences in mean alveolar particle deposition were encountered. The results indicate that in both patient groups the lower-lung regions were most affected by airway obstruction. In patients with peripheral airways disease there was no difference in the degree of right- and left-lung aerosol deposition whereas in patients with COLD obstructive airway alteration was found to affect preferably the right lung region.

This publication has 0 references indexed in Scilit: