Changes in the Vasa Vasorum of the Atherosclerotic Aortic Wall

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Abstract
Human abdominal aortas were studied to determine the changes occurring in the vasa vasorum of atherosclerotic vessels: the transmedial growth of capillaries and anomalies in the walls of the vasa vasorum; and also to examine a possible relationship between intimal vascularization and intimal bleeding. The penetration by vasa vasorum into the wall of atherosclerotic aortas is dependent on the thickness of the wall. The changes in the walls of the vasa vasorum do not precede those in the aorta, and consequently there is no reason to assume that anomalies of the vasa vasorum are a causative factor in the genesis of atherosclerosis. In aneurysms, however, such a relationship may exist. No important relationship was found between intimal vascularization and intimal bleeding.

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