CHANGES IN CORTISOL BINDING AND METABOLISM DURING NEONATAL DEVELOPMENT IN THE GUINEA-PIG
- 1 May 1980
- journal article
- research article
- Published by Bioscientifica in Journal of Endocrinology
- Vol. 85 (2) , 219-227
- https://doi.org/10.1677/joe.0.0850219
Abstract
The metabolic clearance rate and the binding of cortisol in plasma of male and female guinea-pigs were estimated at five stages between birth and weaning. The metabolic clearance rate for cortisol remained low in both sexes until day 10 post partum but increased to adult values by day 20. The level of free cortisol in plasma and the cortisol binding capacity of the plasma were higher at birth than on day 10 post partum; the values found on day 20 were similar to those of the adult guinea-pig. Surgical stress increased levels of cortisol in plasma on day 20 but not at birth.This publication has 2 references indexed in Scilit:
- FOETAL-MATERNAL PRODUCTION AND TRANSFER OF CORTISOL DURING THE LAST DAYS OF GESTATION IN THE GUINEA-PIGJournal of Endocrinology, 1979
- The Half-Life of Hydrocortisone in Normal Newborn InfantsArchives of Pediatrics & Adolescent Medicine, 1960