Absence of Health Hazards Associated with RDX Manufacture and Use

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Abstract
A cross-sectional epidemiologic study was conducted to investigate a cluster of 3 cases of systemic lupus erythematosus at 1 munitions plant. The study demonstrated no excess of autoimmune disease and also failed to identify any abnormalities of the hematologic, hepatic or renal systems in employees with 8 h time-weighted exposures, to RDX [cyclotrimethylene trinitramine, explosive] of up to 1.57 mg/m3 (average exposure was 0.28 mg/m3).

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