Sterol Transmethylation during Aerobic Adaptation of Yeast
Open Access
- 1 April 1974
- journal article
- Published by Wiley in European Journal of Biochemistry
- Vol. 43 (3) , 451-458
- https://doi.org/10.1111/j.1432-1033.1974.tb03431.x
Abstract
An analysis of the total sterol content has been made of a yeast strain during aerobic adaptation. Transmethylation occurs principally at the 4‐demethylsterol level, but conditions were obtained wherein a small fraction of the transmethylations were with 4α‐methyl precursors. Δ7‐Zymostenol has been tentatively identified as a product previously unreported in yeast. Esterification was observed in all sterol intermediates and products. Cell‐free cyclization of 2,3‐epoxy‐22‐methylene squalene to 24‐methylene lanosterol occurs with yeast.Keywords
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