Terferol, an inhibitor of cyclic adenosine 3',5'-monophosphate phosphodiesterase. I Isolation and characterization.
- 1 January 1984
- journal article
- research article
- Published by Japan Antibiotics Research Association in The Journal of Antibiotics
- Vol. 37 (1) , 6-9
- https://doi.org/10.7164/antibiotics.37.6
Abstract
Terferol, a new inhibitor of cyclic adenosine 3', 5'-monophosphate phosphodiesterasc (EC 3.1.4.17, cAMP-PDE), was isolated from the cultured broth of Streptornyces sbowdoensis SANK 65080. It was found to have the molecular formula C19H16O3 and to possess inhibitory activity not only against cAMP-PDE but also against cyclic guanosine 3', 5'-monophosphate phosphodiesterase (cGMP-PDE) from various rat tissues. The terferol concentration required for 50% inhibition of cAMP-PDE was 0.82μM.This publication has 3 references indexed in Scilit:
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- Reticulol, an inhibitor of cyclic adenosine 3',5'-monophosphate phosphodiesterase.The Journal of Antibiotics, 1975
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