Studies on SF-1902 A2-A5, minor components of SF-1902 (globomycin).
- 1 January 1981
- journal article
- research article
- Published by Japan Antibiotics Research Association in The Journal of Antibiotics
- Vol. 34 (11) , 1416-1423
- https://doi.org/10.7164/antibiotics.34.1416
Abstract
Four members of globomycin, SF-1902 A2, A3, A4a and A4b, were newly isolated from the culture of Streptomyces hygroscopicus SF-1902. These minor components shared 4 amino acids in common and the 5th was valine or allo-isoleucine. The fatty acid moiety varied from 3-hydroxy-2-methylheptanoic acid and A2 to 3-hydroxy-2-methylundecanoic acids in A4b. The length of alkyl chain greatly affected the antibacterial activity and maximum activity was shown by the homolog (A5) possessing the longest alkyl chain.This publication has 0 references indexed in Scilit: