Effect in Patients Exposed to Grass Pollen (Sweden)
- 1 January 1984
- journal article
- research article
- Published by Taylor & Francis in Acta Oto-Laryngologica
- Vol. 98 (sup409) , 13-18
- https://doi.org/10.3109/00016488409099011
Abstract
The effect of astemizole 10 mg daily was compared with that of clemastine 3 mg daily in 54 adult patients with seasonal allergic rhinitis in a double-blind study with concomitant pollen count during 4 weeks of the grass pollen season 1982. Similar symptom relieving effects were observed with the two medications together with a tendency towards less sedation with astemizole than with clemastine. No influences on liver or kidney function were found with any of the drugs. A gradual increase of the plasma concentration was observed. The implications of this in treatment of long duration requires further evaluation.Keywords
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