Studies on vaccination against bacillary dysentery. 4. Oral immunization with live monotypic and combined vaccines.

  • 1 January 1968
    • journal article
    • Vol. 39  (3) , 375-80
Abstract
Results of tests made in 1964 confirm the previous findings that live oral vaccine, prepared from streptomycin-dependent strains of shigellae, confers a strong, type-specific protection against acute bacillary dysentery. This vaccine did not reduce the carrier rate of shigellae. Observations on soldiers treated with a vaccine of Shigella flexneri serotypes 2a and 3 combined revealed no antagonizing effects from the type 3 component upon the protective effect of the 2a component contained in the same vaccine.