Decreased Phagolysosomal Fusion of Peripheral Blood Monocytes from Patients with Thalassemia Major
- 1 January 1994
- journal article
- research article
- Published by S. Karger AG in Acta Haematologica
- Vol. 92 (2) , 66-70
- https://doi.org/10.1159/000204177
Abstract
We evaluated the phagolysosomal fusion of peripheral blood monocytes from 15 patients with thalassemia major and 10 thalassemia major carriers using a cytomorphological method with acridine orange as fusion marker. The mono-cyte phagolysosomal fusion of thalassemic patients was decreased (49.6 ± 8.6%, mean ± SD) and differed significantly (pKeywords
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