Electroconvulsive Therapy (With and Without Atropine)
- 1 March 1960
- journal article
- research article
- Published by American Medical Association (AMA) in JAMA Psychiatry
- Vol. 2 (3) , 324-336
- https://doi.org/10.1001/archpsyc.1960.03590090080012
Abstract
Despite the introduction and wide use of psychopharmacologic agents, electroconvulsive therapy (ECT) still is used extensively as the treatment of choice for depressive reactions. This use of ECT is entirely empirical and is not based upon any conclusive data as to the cause of such illness or as to the site of action of ECT. Acceptable evidence is lacking for most of the 50-odd theories of ECT action. One theory that has seemed amenable to investigation is that relating to the importance of the electrocortical response to ECT. This theory states that slow-wave activity is a requisite for ECT to be effective. To date, the data generally have not supported this belief .1-3,11However, Fink and Kahn6have reawakened interest in the therapeutic importance of slow waves by their report of a positive correlation between the degree of EEG slowing and improvement. InKeywords
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