Prospective therapeutic applications of p53 inhibitors
- 2 April 2005
- journal article
- review article
- Published by Elsevier in Biochemical and Biophysical Research Communications
- Vol. 331 (3) , 726-736
- https://doi.org/10.1016/j.bbrc.2005.03.153
Abstract
No abstract availableKeywords
This publication has 96 references indexed in Scilit:
- Dual effect of p53 on radiation sensitivity in vivo: p53 promotes hematopoietic injury, but protects from gastro-intestinal syndrome in miceOncogene, 2004
- Inhibition of p53, p21 and Bax by pifithrin-α does not affect UV induced apoptotic response in CS-B cellsDNA Repair, 2003
- p53 Inhibitor Pifithrin α Can Suppress Heat Shock and Glucocorticoid Signaling PathwaysJournal of Biological Chemistry, 2003
- The C-terminal Fragment of Presenilin 2 Triggers p53-mediated Staurosporine-induced Apoptosis, a Function Independent of the Presenilinase-derived N-terminal CounterpartPublished by Elsevier ,2003
- The role of p53 in determining sensitivity to radiotherapyNature Reviews Cancer, 2003
- Pifithrin-α, an inhibitor of p53, enhances the genetic instability induced by etoposide (VP16) in human lymphoblastoid cells treated in vitroMutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, 2002
- Disruption of p53 in human cancer cells alters the responses to therapeutic agentsJournal of Clinical Investigation, 1999
- Could p53 be a target for therapeutic suppression?Seminars in Cancer Biology, 1998
- Transgenic mice with p53-responsive lacZ: p53activity varies dramatically during normal development and determines radiation and drug sensitivity invivoThe EMBO Journal, 1997
- p53 is required for radiation-induced apoptosis in mouse thymocytesNature, 1993