Down's syndrome associated with two Robertsonian translocations, 45,XX,-15,-21,+t(15q21q) and 46,XX,-21,+t(21q21q)
Open Access
- 1 September 1974
- journal article
- Published by BMJ in Journal of Medical Genetics
- Vol. 11 (3) , 306-309
- https://doi.org/10.1136/jmg.11.3.306
Abstract
A female infant with Down's syndrome was found to be a chromosomal mosaic with two cell lines in both blood and skin cells. One line carried a balanced 15/21 translocation, and the other line was effectively trisomic for chromosome 21 with a 21/21 translocation.Keywords
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