STUDIES ON ANTIBODY PRODUCTION
Open Access
- 1 June 1963
- journal article
- research article
- Published by Rockefeller University Press in The Journal of Experimental Medicine
- Vol. 117 (6) , 1063-1074
- https://doi.org/10.1084/jem.117.6.1063
Abstract
Incorporation of 5-bromodeoxyuridine (BUDR) in the culture medium for the 2nd, 3rd, or 4th day after in vitro antigen stimulation of rabbit popliteal lymph node fragments suppressed the in vitro anamnestic antibody response described previously. Before or after this 3-day period, BUDR had no measurable effect. The results suggest that the antibody response in this in vitro system depends upon cell multiplication during this period.This publication has 21 references indexed in Scilit:
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