Cytotoxicity of ethyl methanesulfonate in mice spermatogonia
- 1 May 1979
- journal article
- research article
- Published by Springer Nature in Cellular and Molecular Life Sciences
- Vol. 35 (5) , 630-631
- https://doi.org/10.1007/bf01960364
Abstract
Summary Enumeration of different types of spermatogonia, following a single i.p. administration of different doses of ethyl methanesulfonate in mice, showed that survival of A1–A4 and in spermatogonia is markedly reduced due to cell killing while the remaining types of spermatogonia were affected marginally. The cell killing effect was dose-dependent, and replenishment of these cells was observed by the end of one cycle of the seminiferous epithelium comprising of 8.5 days.Keywords
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