Hepatocellular carcinoma associated with chronic Schistosoma mansoni infection in a chimpanzee

Abstract
Hepatocellular carcinoma associated with chronic Schistosoma mansoni infection in a chimpanzee, estimated to be a 12‐year‐old and born in West Africa, is reported. The hepatic tumor appeared as a solitary firm nodule, and histological examination revealed well‐differentiated hepatocellular carcinoma with a trabecular pattern. Hepatitis B virus and hepatitis C virus infections were excluded by serological testing in that animal. This is the first report of hepatocellular carcinoma in the chimpanzee with schistosomiasis.