THE ADRENAL CORTICAL HORMONE
- 8 December 1934
- journal article
- research article
- Published by American Medical Association (AMA) in JAMA
- Vol. 103 (23) , 1764-1767
- https://doi.org/10.1001/jama.1934.02750490020005
Abstract
The relatively large number of articles concerning the adrenal1"cortical hormone" that have been published during the past five or six years may lead clinicians to believe that such a hormone has been actually isolated and is available as an effective remedy for treatment of Addison's disease, so-called hypo-adrenalism, and a number of conditions that have no known relationship to the adrenal glands. I am impressed with the lack of proportion between the volume of literature on the subject and the substantial experimental work that it represents. Crude extracts, the composition of which is not known and which contain substances other than the indispensable product of the adrenal cortex, have been extensively used in various experiments from which deductions of far reaching physiologic and clinical significance have been readily made. Reports have been published on alleged remarkable beneficial influence of such extracts in the treatment of Addison's disease and a number of otherKeywords
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