Minimally invasive stereotactic puncture and thrombolysis therapy improves long-term outcome after acute intracerebral hemorrhage
Open Access
- 22 February 2011
- journal article
- clinical trial
- Published by Springer Nature in Zeitschrift für Neurologie
- Vol. 258 (4) , 661-669
- https://doi.org/10.1007/s00415-011-5902-7
Abstract
The purpose of this study was to judge the clinical value of minimally invasive stereotactic puncture and thrombolysis therapy (MISPTT) for acute intracerebral hemorrhage (ICH). A randomized control clinical trial was undertaken. According to the enrollment criteria, 122 acute ICH cases were analyzed, of which 64 cases received MISPTT (MISPTT group, MG) and 58 cases received conventional craniotomy (CC group, CG). The Glasgow coma scale (GCS) scores, postoperative complications (PC), and rebleeding incidences were compared. Moreover, 1 year postoperation, the long-term outcomes of patients with regard to hematoma volume (HV) P = 0.243). There were no obvious differences between the CFs of MG and CG (17.2 and 25.9%, respectively, P = 0.199). The GOS, BI, and mRS representing long-term outcome for both HV P < 0.05). These data suggest that there are advantages with MISPTT not only in trauma and safety, but the MISPTT group had fewer complications and a trend toward improved short-term and long-term outcomes.Keywords
This publication has 36 references indexed in Scilit:
- Characterization of Acute Brain Injuries and Neurobehavioral Profiles in a Rabbit Model of Germinal Matrix HemorrhageStroke, 2008
- Stereotactic Aspiration-Thrombolysis of Intracerebral Hemorrhage and its Impact on Perihematoma Brain EdemaNeurocritical Care, 2008
- Guidelines for the Management of Spontaneous Intracerebral Hemorrhage in AdultsStroke, 2007
- Iron and Iron-Handling Proteins in the Brain After Intracerebral HemorrhageStroke, 2003
- Experimental Intracerebral Hemorrhage in the MouseStroke, 2003
- Stereotactic Treatment of Intracerebral Hematoma by Means of a Plasminogen ActivatorStroke, 2003
- Stereotactic Computed Tomographic–Guided Aspiration and Thrombolysis of Intracerebral HematomaStroke, 2000
- Surgery for Primary Intracerebral Hemorrhage: Is It Safe and Effective?Stroke, 1997
- Early Hemorrhage Growth in Patients With Intracerebral HemorrhageStroke, 1997
- The ABCs of Measuring Intracerebral Hemorrhage VolumesStroke, 1996