THE USE AND INTERPRETATION OF TESTS FOR LIVER FUNCTION

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Abstract
For twenty years or more clinicians, physiologists and clinical pathologists have attempted to devise procedures or tests that would indicate the functional capacity of the liver, in order to determine the presence and degree of disease of the liver and to obtain information with regard to prognosis. The careful physiologic studies that have been made following total and partial hepatectomy have served as a guide to the solution of this problem and have stimulated interest in it. Meanwhile, physiologists repeatedly have warned that no one function could be depended on to indicate the general status of the whole organ and that the reserve function of the liver was so great that functional abnormalities could be expected to appear only when most of it had been destroyed. In presenting the following report, it is our intention to consider the utility and general significance of the tests in common use and to

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