The Latest Progress in the Synthesis of Carbocyclic Nucleosides
- 1 March 2000
- journal article
- review article
- Published by Taylor & Francis in Nucleosides, Nucleotides and Nucleic Acids
- Vol. 19 (3) , 651-690
- https://doi.org/10.1080/15257770008035015
Abstract
This review presents the latest developments in the field of carba-nucleosides (1994–1998). Special attention is paid to the synthesis of key precursors to those carba-nucleosides that possess significant biological activities or have novel structures.Keywords
This publication has 126 references indexed in Scilit:
- Asymmetric synthesis and anti-HIV activity of L-carbocyclic 2′,3′-didehydro-2′,3′-dideoxyadenosineBioorganic & Medicinal Chemistry Letters, 1998
- A Methylated Derivative of 5‘-NoraristeromycinThe Journal of Organic Chemistry, 1997
- An expeditious route to carbocyclic nucleosides: (−)-aristeromycin and (−)-carbodineBioorganic & Medicinal Chemistry Letters, 1997
- Synthesis and Anti-Trypanosomal Activity of Various 8-Aza-7-deaza-5‘-noraristeromycin DerivativesJournal of Medicinal Chemistry, 1997
- Highly Efficient and Enantioselective Synthesis of Carbocyclic Nucleoside Analogs Using Selective Early Transition Metal CatalysisThe Journal of Organic Chemistry, 1996
- Synthesis of Enantiomerically Pure Bis(hydroxymethyl)-Branched Cyclohexenyl and Cyclohexyl Purines as Potential Inhibitors of HIVThe Journal of Organic Chemistry, 1996
- Enantioselective Synthesis of (1R,4S)-1-Amino-4-(hydroxymethyl)-2-cyclopentene, a Precursor for Carbocyclic Nucleoside SynthesisThe Journal of Organic Chemistry, 1994
- Synthesis of hydroxylated cyclohexenyl- and cyclohexanyladenines as potential inhibitors of S-adenosylhomocysteine hydrolaseThe Journal of Organic Chemistry, 1992
- Resolution of racemic carbovir and selective inhibition of human immunodeficiency virus by the (−) enantiomerBiochemical and Biophysical Research Communications, 1990
- Potent and selective activity of a new carbocyclic nucleoside analog (Carbovir: NSC 614846) against human immunodeficiency virus In vitroBiochemical and Biophysical Research Communications, 1988