Cystic Fibrosis: Characterization of the Inhibitor to Ciliary Action in Oyster Gills
- 6 February 1970
- journal article
- other
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 167 (3919) , 871-873
- https://doi.org/10.1126/science.167.3919.871
Abstract
The inhibitor to oyster ciliary activity was isolated from serum of cystic fibrosis patients and heterozygotes. The inhibiting protein fraction was a cation as judged by electrophoresis; it had a molecular weight of 125,000 to 200,000 as judged by gel filtration; and on diethylaminoethyl-cellulose chromatography it eluted with the immunoglobulin G fraction. The analogous fraction in normal individuals did not inhibit oyster cillary activity.Keywords
This publication has 5 references indexed in Scilit:
- Inhibition of the motility of gill cilia of Dreissensia by plasma of cystic fibrosis patients and their parents.Journal of Medical Genetics, 1969
- Oyster Ciliary Inhibition by Cystic Fibrosis FactorScience, 1969
- Abnormal Serum Factor in Patients with Cystic Fibrosis of the PancreasPediatric Research, 1967
- Estimation of the molecular weights of proteins by Sephadex gel-filtrationBiochemical Journal, 1964
- CHROMATOGRAPHY OF PROTEINS ON CELLULOSE ION-EXCHANGERSJournal of the American Chemical Society, 1954