EFFECTS OF TOPICAL INSTILLATION OF ADRIAMYCIN IN BLADDER TUMORS OF RATS FED WITH FANFT

  • 1 January 1978
    • journal article
    • research article
    • Vol. 15  (4) , 278-279
Abstract
Topical bladder instillation of adriamycin was evaluated against rat tumors produced by diets containing FANFT (N-[4-(5-nitro-2-furyl)-2-thiazolyl] formamide). The drug was ineffective in either preventing or eradicating tumors. The failure of response in this animal model may be related to drug schedule, biological potential of this tumor or ineffectiveness of adriamycin in this tumor.